Blog
How automated workflows simplify NGS analysis
NGS Data Analysis Bottlenecks One of the biggest bottlenecks in next generation sequencing (NGS) today is data analysis, which is surprising, considering that we have massive compute available at our fingertips, the available infrastructure to process thousands of...
Use of NGS in Cell and Gene Therapy
Introduction Cell and gene therapy have emerged as promising approaches for the treatment of various diseases. These innovative therapies involve manipulating cells or genes to restore or enhance their function. Next-Generation Sequencing (NGS) plays a crucial role in...
A Comprehensive Guide to Analyze Single-Cell RNA Sequencing Data
How to Analyze Single-Cell RNA Sequencing Data: A Comprehensive GuideIntroduction The first step in analyzing scRNA-seq data is to understand the biology behind the experiment. scRNA-seq generates gene expression data for each cell, which can be used to identify cell...
Achieving data provenance with Basepair’s automated audit trails
When Auditing goes wrong Is your genomics team keeping track of the open source tools it’s using? What about software version numbers and the parameters being set? Genome reference files, usage logs, the custom scripts bioinformaticians are deploying? If you’re not...
Visualizing your NGS results with Basepair
Writers write, painters paint, genomics researchers… wait patiently for bioinformatics pipelines to finish processing NGS data, only to spend as much time visualizing results? As long-time researchers and bioinformaticians, we’re well aware that in NGS data analysis,...
Pathway Enrichment Analysis for ChIP-seq Data
As you may already know, Basepair offers a number of very popular tools for ChIP-seq analysis, seamlessly taking your FASTQ files to meaningful results. From trimming and alignment, peak calling and annotation, to motif enrichment and now, pathway enrichment analysis...