Blog
Cows, Computers, and the Art of Working Remotely
There are among us a few gurus who have long perfected the art of working remotely. These are the people who already had a home office setup and didn't need to buy an office chair or an extra monitor on Amazon a couple months back. They have long possessed the...
SARS-CoV-2 Genome and Pipeline Now on Basepair
If your lab or company is working with COVID-19 data, Basepair is ready to handle your analysis needs. We do this in two ways: You can use our existing infrastructure and pipelines to run your analyses. The SARS-CoV-2 genome is already available on Basepair. If you...
Large projects with hundreds of samples? Try these fully automated upload options on Basepair
Basepair has an easy-to-use upload page that is ideal for the majority of our users. Select the samples you want to upload from your local computer, specify the sample metadata, and start the upload. Samples upload as fast as your internet connection allows. But what...
Trimming for RNA-Seq data
Quality trimming decreases the overall number of reads, but increases to the total and proportion of uniquely mapped reads. Thus, you get more useful data for downstream analyses. Too aggressive quality trimming can negatively impact downstream analysis (in our example, estimation of gene expression). Hence, our own findings and that of the research community motivate the incorporation of a light amount of trimming in RNA-seq data (we use a Q threshold of 10).
Basepair Awarded $300,000 Grant for Development of Software Platform for Pre-Implantation Genetic Testing
The Eunice Kennedy Shriver National Institute of Child Health & Human Development recently awarded Basepair a $300,000 Small Business Innovation Research grant for the development of a software platform for pre-implantation genetic testing of aneuploidy (PGT-A). ...
Introducing Basepair’s differential alternative splicing pipeline
We are pleased to announce the release of our new pipeline for investigating changes in alternative splicing (AS) in RNA-seq. As a quick reminder, a gene may have many forms (isoforms) depending on which exons and transcription...